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Adegen
Prescription Extra Strength
ARB Topical A15 is Adegen's highest-strength prescription topical, three times the minoxidil concentration of A5 in the same measured 1 mL application. It combines 15% minoxidil with our proprietary ARB complex, plus tretinoin, caffeine, and a niacinamide + biotin blend to support absorption and overall follicle health.
Compounded in-house at Adegen Pharmacy and formulated to help key ingredients reach the follicle, where healthy hair growth begins, A15 is built for more noticeable thinning, slower response to standard-strength treatment, or anyone who wants maximum topical support.
Optional Rx DHT Blockers
You can optionally add topical finasteride or dutasteride for added DHT defense. Finasteride inhibits the primary enzyme (Type II) responsible for converting testosterone to DHT in the scalp. Dutasteride inhibits both Type I and Type II enzymes, for broader, stronger DHT reduction.
Full Formulation
ARB Proprietary Complex (designed to support the androgen receptor and follicle environment)
Micronized Minoxidil 15% (150 mg/mL)
Caffeine 0.2% (2 mg/mL)
Niacinamide + Biotin Blend 0.3% (3 mg/mL)
Tretinoin 0.01% (0.1 mg/mL)
Delivered via proprietary DermalDrive™ topical delivery system
Best For Moderate to advanced thinning or hair loss, slower response to 5% formulas, and anyone who wants maximum-strength topical support.
Safety & Rx Information This is a prescription-only compounded medication dispensed through Adegen Pharmacy, our licensed 503A compounding pharmacy. A licensed physician will review your information after checkout and determine if this formula is appropriate for you.
Apply 1 mL (10 sprays) to thinning or affected areas of the scalp once to twice daily, or as directed by your licensed physician. Each spray delivers approximately 0.1 mL (10 sprays = 1 mL). Gently massage in with one finger.
Exfoliation Brush
A precision scalp massage brush that stimulates circulation and exfoliates the scalp for better absorption.
Exfoliation Brush
A precision scalp massage brush that stimulates circulation and exfoliates the scalp for better absorption.
HOW IT WORKS
Everyday Regrowth
Extra Strength Regrowth
~70% DHT Reduction
~90% DHT Reduction
A scalp-first formula designed to support better delivery, healthier follicles, and stronger-looking hair.
Works at the scalp level to deliver active ingredients where hair growth begins.
Supports better delivery into the scalp so treatment can reach the follicle more effectively.
Helps support fuller-looking, healthier hair with consistent use over time.
Designed for simple daily use, making it easier to stay consistent and see progress.
“I tried everything before Adegen. Nothing worked—until now. I am so grateful to John and Adegen group for changing my life!”
"At day 49 I almost didn't take progress photos — I didn't think anything was happening. 11.5 months later, my hairdresser couldn't stop uncovering layers of new growth. I've never been happier about a bad hair day in my life."
“I couldn't be more ecstatic with the results. I have been using it for 5 months and I am seeing results that I never thought were possible. This has been a miracle solution, Adegen has been godsend to me, I'm so grateful!”
“I am happy with how healthy my hair is! Sometimes when I feel it isn't happening fast enough I have to go back to the day I was about to shave my head.”
“Honestly 3 months after using Adegen everything was completely different. May hairline started to fill up and my crown is filling like crazy. For the first time I am happy and confident on how my hair looks! I'm so gratful for this product”
“It’s not just my hairline that has gotten way better, but all of my hair is thicker and healthier than ever. These photos are only 6 months apart.Thank you Adegen!”
“It's been a little over 3 months of using the topical and under 3 months of using the shampoo and I'm pretty stocked about the results!”
“I was skeptical after trying everything on the market. After 3 months on Adegen, my hairline has visibly filled in. I finally feel confident again.”
Free from unnecessary fillers, heavy silicones, and harsh detergents. Every ingredient is chosen to support a healthier scalp environment and more effective follicle-level delivery.
ARB Proprietary Complex
A targeted complex designed to support the androgen receptor and follicle environment. By working at the follicle, it creates the foundation the rest of the formula builds on.
Micronized Minoxidil
Milled to under 10 microns for deeper scalp penetration and more effective follicle-level delivery. Smaller particles help the formula reach where regrowth support actually begins.
Tretinoin
Supports healthy scalp cell turnover while helping improve the absorption of key actives. It helps renew the scalp environment so the formula can work more effectively.
Caffeine
Helps support circulation around the follicle to improve the delivery of oxygen and nutrients. It also helps energize the scalp and support a healthier growth cycle.
Niacinamide + Biotin
A blend of nourishing B vitamins that support a balanced scalp and stronger-looking hair, reinforcing the environment healthy hair depends on.
Finasteride (add on)
Available as an Rx add-on, this topical active helps reduce DHT at the source by inhibiting 5-alpha reductase. Paired with ARB, it supports a more complete follicle-level approach to DHT management.
Dutasteride (add on)
Available as an Rx add-on, this more potent active helps reduce DHT by blocking both Type 1 and Type 2 conversion pathways. Combined with ARB, it offers the most comprehensive follicle-level DHT support in the lineup.
A side-by-side look at why Adegen stands apart, from formulation
ownership to follicle-level delivery.
100% in-house development by the team that pioneered the original 15% minoxidil formula.
ARB technology, DermalDrive™ delivery, and CryoSafe™ no-heat compounding.
USP Compendial Grade Dutasteride, Tretinoin, Micronized Minoxidil, Caffeine and more.
DermalDrive™ advanced delivery system engineered to drive micronized actives deep into the follicle.
Precision Applicator for fast, even, targeted scalp coverage. Complete System.
Compounded and shipped in-house for greater control over quality, consistency, and potency.
Generic third-party formulas with no direct formulation ownership.
Decades-old formulas with no innovation in formulation technology.
Commodity-grade actives at lower strengths with fewer performance-focused ingredients.
Standard solvents. Large particles that mostly sit on the surface.
Generic droppers: imprecise application, uneven scalp coverage, and product waste.
Outsourced to third-party pharmacies. Limited control over quality, consistency, and innovation.
100% in-house development by the team that pioneered the original 15% minoxidil formula.
Generic third-party formulas with no direct formulation ownership.
ARB technology, DermalDrive™ delivery, and CryoSafe™ no-heat compounding.
Decades-old formulas with no innovation in formulation technology.
USP Compendial Grade Dutasteride, Tretinoin, Micronized Minoxidil, Caffeine and more.
Commodity-grade actives at lower strengths with fewer performance-focused ingredients.
DermalDrive™ advanced delivery system engineered to drive micronized actives deep into the follicle.
Standard solvents. Large particles that mostly sit on the surface.
Precision Applicator for fast, even, targeted scalp coverage. Complete System.
Generic droppers: imprecise application, uneven scalp coverage, and product waste.
Compounded and shipped in-house for greater control over quality, consistency, and potency.
Outsourced to third-party pharmacies. Limited control over quality, consistency, and innovation.
Adegen starts working from day one, but visible results take time and consistency. Most people begin to notice changes around 90 days, and results continue to improve over the months and even years that follow.
Adegen is not a basic hair loss product. It is a prescription-grade system designed to target the key drivers of follicle weakening, including poor circulation, DHT activity, and inefficient follicular delivery. Powered by 15% micronized minoxidil, ARB technology, dutasteride, caffeine, tretinoin, and more, Adegen delivers a more comprehensive approach than conventional hair loss treatments.
Hair loss is an ongoing biological process, so maintaining results requires consistent care, much like diet, exercise, or oral health. Continued use of Adegen helps support circulation, follicle health, and the natural hair growth cycle, making it a simple part of your long-term hair maintenance routine.
A hair transplant moves existing follicles but doesn't stop the hair loss underneath, so results often fade without treating the root cause. That's why we recommend the full Adegen system first, usually three to six months. It strengthens your follicles for a better result with fewer grafts, and some people find they need fewer than planned, or no transplant at all. Watch John, who had a transplant himself, explain why.
Much of the fear around hair loss treatment online is louder than the evidence supports. Our topical system works at the scalp, and our oral options are prescription medications reviewed by a licensed physician who walks you through the real risks and benefits for your situation. Most people tolerate treatment well, and your physician can tailor your plan if any concerns come up. For men who want added peace of mind, we also offer daily tadalafil to support circulation and sexual health. Watch John break down what the research actually says.
Yes, and many do. Women's hair loss often traces to the same root cause as men's: restricted blood flow to the follicle. Many women see excellent results, and our HairIQ assessment builds a protocol suited specifically to them. We've helped women from their twenties into their eighties. Watch John explain why Adegen works so well for women.
When I first ordered the ARB topical – 15 it came with the eyedropper. I used it along with the roller. Other products I had used previously did not mention anything about preparing your scalp first. I truly believe the needle roller is an important tool you should keep consistent in your hair routine. After a few orders
I received my order of ARB topical 15 with a “spray attachment.” Wow this was a game changer!! thank you so much for sending my order with the spray attachment. So I’ve been using the ARB topical 15 since January 2026. It’s now June and my hair regrowth has been phenomenal. The side effects were a little frightening and I have to admit I was a little sloppy in applying the application to the crown of my head and sides. Sometimes I had not let the topical dry before going to bed. I did use a cloth on my pillowcase, but while sleeping you don’t notice where your head and face are laying so the left side of my face grew a little more hair than I had expected. That was my experience in the beginning. After months 2 and 3, I almost stopped using the product because everyday I was experiencing more hair loss than I expected. But I hung in there and kept being consistent. Even though my hairline was showing growth I was very concerned about the amount of loss. Month 4 was my plateau. Hair shedding started to slow down and by month 6, stopped completely. After learning the hard way, I am pleased with the process. Thank you John Goss and team for…
I've tried everything from Minoxidil and Finasteride to Carbon monoxide shampoo and rubber scalp scrubbers, and my hairline kept receding. Finally, I see this ad of John Goss pop up in my news feed, explaining that so had he. I figured I had nothing to lose, so I tried the three month supply and faithfully used the scrubbers, shampoo and serum without even paying attention to whether I'd been making progress. One day, my wife asks if I'd noticed my hair recently, which led me to a mirror and noticed a thicker head of hair. I poured through my photos and was astonished to realize exactly how thin my hair had gotten when I'd started, and how remarkably full it had become! Adegen, you've earned yourself a customer for life!
Hi Kurt, thank you so much for sharing such an incredible and detailed experience with the ARB Complete Regrowth Kit!
Your journey really resonates with us - trying various solutions without success can be so frustrating, and we're absolutely happy that you decided to give Adegen a chance after seeing John's story. It's amazing how your wife noticed the difference before you did - that kind of observation from someone who sees you every day really speaks to the remarkable progress you've made!
Your story about going from skeptical to "customer for life" after trying everything else really means the world to us. We're so happy that Adegen finally gave you the results you were looking for!
It is worth a go, and I recommend holding off judgement until you are at least 3 months in! l am a 62 year old woman who had diffuse thinning that I started noticing at least 10 years ago- probably longer. I tried lots of things- Hair Club sessions, Minoxidil, PRP, a formula from Italy... cosmetic, too- SMP, extensions... I have been using Adegen for about a year and a half, and I have no visible thinning, and haven't for quite some time. I have always used Topical 15, and when I wash my hair (every 2-3 days), I work the shampoo in and LET IT SIT - often for 30 minutes or more - before washing it out. I am convinced this part is extremely effective. Good luck!
My barber recommended Adegen to me because one of his other clients used it. So I bought your product and have been using it for about a month and a half. I'm seeing great results so far! In fact, my barber is so impressed, he ordered the product for himself!
I'm Seeing Some Results I switched from ARB -5 to ARB -15- my hairline is seeing some hairs starting to fill in, and the top of my head is slightly thickening. I'm very diligent about using the products, scalp massage, and rolling about 3 times a week. It's making a difference. John, you seem very trustworthy!
tried Hairclub before but I wasn't getting very good results. I came across Adegen on the mind valley podcast. I was losing hair around the temples and my goal with adegen was really just to regrow hair around the edges of the receding area. In reality though, I am actually regrowing where there was basically just bare skin left. It's been a long process but it's worth it. I'm using the 15X
Topical I've been using the topical 15x now for 4 months or so, I'm using it the product less than 30 days, I don't believe I'm using too much? I wish the bottle was a little bit bigger! No new hair growth but my hair has noticeably been a lot fuller and thicker, trust me I know it's a process! I'm trusting the process lol , faithfully
